PubMed ID: 35619185 Author(s): Mavlyutov TA, Myrah JJ, Chauhan AK, Liu Y, McDowell CM. Fibronectin extra domain A (FN-EDA) causes glaucomatous trabecular meshwork, retina, and optic nerve damage in mice. Cell Biosci. 2022 May 26;12(1):72. …
Publications
A20 Attenuates the Fibrotic Response in the Trabecular Meshwork.
PubMed ID: 35216043 Author(s): Mzyk P, Zalog EG, McDowell CM. A20 attenuates the fibrotic response in the trabecular meshwork. Int J Mol Sci. 2022 Feb 9;23(4). pii: 1928. doi: 10.3390/ijms23041928. PMID 35216043 Journal: International Journal …
Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms.
PubMed ID: 35129590 Author(s): McDowell CM, Kizhatil K, Elliott MH, Overby DR, van Batenburg-Sherwood J, Millar JC, Kuehn MH, Zode G, Acott TS, Anderson MG, Bhattacharya SK, Bertrand JA, Borras T, Bovenkamp DE, Cheng L, …
TLR4 signaling modulates extracellular matrix production in the lamina cribrosa.
PubMed ID: 36911656 Author(s): Geiduschek EK, Milne PD, Mzyk P, Mavlyutov TA, McDowell CM. TLR4 signaling modulates extracellular matrix production in the lamina cribrosa. Front Ophthalmol (Lausanne). 2022;2:968381. doi: 10.3389/fopht.2022.968381. Epub 2022 Aug 19. PMID …
Toll-Like Receptor 4 Signaling in the Trabecular Meshwork.
PubMed ID: 35912101 Author(s): Mzyk P, Hernandez H, Le T, Ramirez JR, McDowell CM. Toll-Like Receptor 4 Signaling in the Trabecular Meshwork. Front Cell Dev Biol. 2022 Jul 15;10:936115. doi: 10.3389/fcell.2022.936115. eCollection 2022. Review. PMID …
Caffeine Inhibits Choroidal Neovascularization Through Mitigation of Inflammatory and Angiogenesis Activities.
PubMed ID: 34722519 Author(s): Sorenson CM, Song YS, Zaitoun IS, Wang S, Hanna BA, Darjatmoko SR, Gurel Z, Fisk DL, McDowell CM, McAdams RM, Sheibani N. Caffeine Inhibits Choroidal Neovascularization Through Mitigation of Inflammatory and …
Fibronectin extra domain A (FN-EDA) elevates intraocular pressure through Toll-like receptor 4 signaling.
PubMed ID: 32555351 Author(s): Roberts AL, Mavlyutov TA, Perlmutter TE, Curry SM, Harris SL, Chauhan AK, McDowell CM. Fibronectin extra domain A (FN-EDA) elevates intraocular pressure through Toll-like receptor 4 signaling. Sci Rep. 2020 Jun …
Effects of Toll-Like Receptor 4 Inhibition on Transforming Growth Factor-β2 Signaling in the Human Trabecular Meshwork.
PubMed ID: 31834824 Author(s): Sharma TP, Curry S, McDowell CM. Effects of toll-like receptor 4 inhibition on transforming growth factor-β2 signaling in the human trabecular meshwork. J Ocul Pharmacol Ther. 2020 Apr;36(3):170-178. doi: 10.1089/jop.2019.0076. Epub …
Nuclear factor-kappa beta signaling is required for transforming growth factor Beta-2 induced ocular hypertension.
PubMed ID: 31923415 Author(s): Hernandez H, Roberts AL, McDowell CM. Nuclear factor-kappa beta signaling is required for transforming growth factor Beta-2 induced ocular hypertension. Exp Eye Res. 2020 Feb;191:107920. doi: 10.1016/j.exer.2020.107920. Epub 2020 Jan 8. …
Disruption of fibronectin fibrillogenesis affects intraocular pressure (IOP) in BALB/cJ mice.
PubMed ID: 32822410 Author(s): Faralli JA, Filla MS, McDowell CM, Peters DM. Disruption of fibronectin fibrillogenesis affects intraocular pressure (IOP) in BALB/cJ mice. PLoS One. 2020 Aug 21;15(8):e0237932. doi: 10.1371/journal.pone.0237932. eCollection 2020. PMID 32822410 Journal: …